Thermo Fisher Scientific human Fibrinogen Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

ELISA (ELISA)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Fibrinogen from human plasma. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Fibrinogen,uniProtId:P02671-1,ncbiNodeId:9606,antigenRange:1-866,antigenLength:866,antigenImageFileName:BS-1240G_Fibrinogen_P02671-1_Goat.svg,antigenImageFileNamePDP:BS-1240G_Fibrinogen_P02671-1_Goat_PDP.jpeg,sortOrder:1},{targetFamily:Fibrinogen,uniProtId:P02675-1,ncbiNodeId:9606,antigenRange:1-491,antigenLength:491,antigenImageFileName:BS-1240G_Fibrinogen_P02675-1_Goat.svg,antigenImageFileNamePDP:BS-1240G_Fibrinogen_P02675-1_Goat_PDP.jpeg,sortOrder:2},{targetFamily:Fibrinogen,uniProtId:P02679-1,ncbiNodeId:9606,antigenRange:1-453,antigenLength:453,antigenImageFileName:BS-1240G_Fibrinogen_P02679-1_Goat.svg,antigenImageFileNamePDP:BS-1240G_Fibrinogen_P02679-1_Goat_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.