
Thermo Fisher Scientific GTF2B Monoclonal Antibody (IIB8)
Human 및 Mouse 시료에서 Transcription Factor IIB 검출용 단클론 항체. ELISA, Western blot, Immunoprecipitation에 사용 가능. Recombinant human TFIIB를 면역원으로 제작된 Unconjugated 형식. 고순도 정제 및 PBS buffer 보존, 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–10 µg/mL |
| ELISA | 1–10 µg/mL |
| Immunoprecipitation (IP) | 1–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IIB8 |
| Immunogen | Recombinant human transcription factor IIB (TFIIB) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | ~1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2114364 |
Product Specific Information
MA1-10884 detects Transcription Factor IIB from human and mouse samples.
This antibody has been successfully used in ELISA, Western blot, and immunoprecipitation applications.
The immunogen used is recombinant human transcription factor IIB (TFIIB).
Target Information
Ubiquitin is a 76-amino-acid, highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome.
The ubiquitination process regulates the concentration of key cellular proteins by controlling their lifespans.
Polyubiquitination involves serial steps: activation of ubiquitin via ATP-dependent formation of a thioester bond with E1 enzyme, transfer to E2 conjugating enzyme, and covalent linkage to target proteins directly or via E3 ligase.
Deubiquitination enzymes can reverse this marking.
Ubiquitin tagging is involved in numerous cellular processes including cell cycle, growth, differentiation, apoptosis, signal transduction, DNA repair, transcription regulation, transport, stress response, immune response, and nervous system function.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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