Thermo Fisher Scientific NPR3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NPR3, validated for Western blot and IHC. Recognizes recombinant NPR3 protein with high cross-species homology. Supplied as liquid, unconjugated form, 0.05 mg/mL concentration. Suitable for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (IHC) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NPR3 (amino acids 163–302) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644776 |
Product Specific Information
Immunogen sequence:
GFQHKDSEYS HLTRVAPAYA KMGEMMLALF RHHHWSRAAL VYSDDKLERN CYFTLEGVHE VFQEEGLHTS IYSFDETKDL DLEDIVRNIQ ASERVVIMCA SSDTIRSIML VAHRHGMTSG DYAFFNIELF NSSSYGDGSW
Antigen sequence identity:
- Mouse: 93%
- Rat: 92%
Target Information
This gene encodes one of three natriuretic peptide receptors. Natriuretic peptides regulate blood volume, blood pressure, pulmonary hypertension, cardiac function, and various metabolic and growth processes. The NPR3 receptor mediates clearance of circulating and extracellular natriuretic peptides through endocytosis. Multiple transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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