Thermo Fisher Scientific MLPH Monoclonal Antibody (OTI6E8), TrueMAB
MLPH 단백질을 인식하는 Mouse monoclonal 항체로 Western blot과 IHC(Paraffin)에서 검증됨. Human 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공. Affinity chromatography로 정제되었으며, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 295–600 of human MLPH produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Slac2-a (synaptotagmin-like protein homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes.
Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), located near the N-terminus.
The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex. Mutations in the binding domains of these protein components may cause albinism and/or severe immune disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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