Thermo Fisher Scientific DCC Polyclonal Antibody, FITC
FITC로 표지된 DCC 폴리클로날 항체로 인간, 마우스, 랫트 반응성. WB, ELISA, IP 등 다양한 응용에 적합. 합성 펩타이드 면역원 사용, 친화 크로마토그래피로 정제. 형광 특성은 498/517 nm, 연구용으로만 사용.
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Thermo Fisher Scientific DCC Polyclonal Antibody, FITC
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
- ELISA: 1:10,000
- Immunoprecipitation (IP): 1:50–1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1330–1380 on rat DCC protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a netrin 1 receptor, a transmembrane protein belonging to the immunoglobulin superfamily of cell adhesion molecules. It mediates axon guidance of neuronal growth cones toward sources of netrin 1 ligand. The cytoplasmic tail interacts with tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts and induces apoptosis in the absence of ligand. It functions as a tumor suppressor and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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