Thermo Fisher Scientific MAP4 Polyclonal Antibody
Human MAP4 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공됩니다. 세포골격 연구 및 미세소관 관련 단백질 분석에 유용합니다.
- 카탈로그번호
- PA558273
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MAP4. Recombinant protein control fragment (Product #RP-96263). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643742 |
Product Specific Information
Immunogen sequence:
PPAQALEIMM GLKTTDMAPS KETEMALAKD MALATKTEVA LAKDMESPTK LDVTLAKDMQ PSMESDMALV KDMELPTEKE VALVKDVRWP TETDVSSAKN VV
Sequence identity with orthologs:
- Mouse: 48%
- Rat: 47%
Target Information
The MAP4 gene encodes a major non-neuronal microtubule-associated protein. It contains a domain similar to those of MAP2 and MAPT (tau) proteins. MAP4 promotes microtubule assembly and counteracts microtubule destabilization. It interacts with Cyclin B to target CDC2 kinase to microtubules, influencing phosphorylation, microtubule dynamics, and cell cycle progression. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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