
Thermo Fisher Scientific DCLK1 Polyclonal Antibody
DCLK1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, 인간 및 생쥐 시료에 반응합니다. Western blot에 적합하며, 고순도의 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DCLK1 (Accession O15075), corresponding to amino acid residues T688–S738 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899736 |
Product Specific Information
This antibody detects endogenous levels of total DCLK1.
Target Information
DCAMKL1 (DCLK1), also known as doublecortin-like kinase 1, is a serine/threonine kinase containing two N-terminal doublecortin domains that bind microtubules and regulate microtubule polymerization. It also has a C-terminal serine/threonine protein kinase domain homologous to Ca²⁺/calmodulin-dependent protein kinase and a serine/proline-rich domain that mediates multiple protein–protein interactions.
DCLK1 is a microtubule-associated kinase capable of autophosphorylation and has microtubule-polymerizing activity independent of its kinase activity. It is involved in neuronal migration, retrograde transport, neuronal apoptosis, and neurogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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