Thermo Fisher Scientific DCLK1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:3,000

Product Specifications

Product Specific Information

This antibody detects endogenous levels of total DCLK1.

Target Information

DCAMKL1 (DCLK1), also known as doublecortin-like kinase 1, is a serine/threonine kinase containing two N-terminal doublecortin domains that bind microtubules and regulate microtubule polymerization. It also has a C-terminal serine/threonine protein kinase domain homologous to Ca²⁺/calmodulin-dependent protein kinase and a serine/proline-rich domain that mediates multiple protein–protein interactions.
DCLK1 is a microtubule-associated kinase capable of autophosphorylation and has microtubule-polymerizing activity independent of its kinase activity. It is involved in neuronal migration, retrograde transport, neuronal apoptosis, and neurogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.