Thermo Fisher Scientific ABCC11 Polyclonal Antibody
ABCC11 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. 합성 펩타이드 면역원 기반, 고순도, 액상 형태로 연구용에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KVVEFDRPEVLRK) corresponding to the internal amino acids of ABCC11 (aa 1352–1364) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10977039 |
Product Specific Information
- This antibody is predicted to react with canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes.
ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This ABC full transporter is a member of the MRP subfamily involved in multi-drug resistance.
The gene product participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides.
A SNP in this gene determines human earwax type.
ABCC11 and its family member ABCC12 are derived by duplication and both localized to chromosome 16q12.1.
Multiple alternatively spliced transcript variants have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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