Thermo Fisher Scientific Ras (Q61R Mutant) Polyclonal Antibody
Ras(Q61R Mutant)에 특이적인 Rabbit Polyclonal Antibody로 Western blot에 적합. Human에 반응하며 다양한 종에서 예측 반응성 보유. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:3,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human N-Ras (Q61R). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.14 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736505 |
Product Specific Information
- Positive Control: Myc-DDK-human RAS (mutant Q61R)-transfected 293T
- Predicted Reactivity: Mouse, Rat, Zebrafish, Xenopus laevis, Dog, Pig, Chicken, Bovine, Guinea pig (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Ras is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. The process of shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in the Ras gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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