Thermo Fisher Scientific KCTD15 Polyclonal Antibody
Rabbit polyclonal antibody against human KCTD15 protein. Validated for ICC/IF applications with high specificity. Supplied as liquid in PBS with glycerol and sodium azide. Suitable for research use in obesity-related genetic studies.
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Applications and Tested Dilution
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 1–45). Recombinant protein control fragment: Product #RP-99118 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091980 |
Product Specific Information
- Immunogen sequence: MPHRKERPSG SSLHTHGSTG TAEGGNMSRL SLTRSPVSPL AAQGI
- Antigen sequence identity: Mouse 93%; Rat 93%
Target Information
Childhood and adult obesity have increased dramatically worldwide over the past decade, driven by both environmental and genetic factors. The potassium channel KCTD15 gene has been identified as a locus associated with higher body mass index (BMI) in humans, along with GNPDA2, MTCH2, FTO, and TMEM18.
Further studies on single nucleotide polymorphisms (SNPs) in diabetic and non-diabetic patients showed FTO as most strongly associated with obesity, while MTCH2 and GNPDA2 also showed significant associations with elevated BMI.
At least two isoforms of KCTD15 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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