Thermo Fisher Scientific IL12RB1 Polyclonal Antibody
인간 IL12RB1 단백질을 인식하는 토끼 폴리클로날 항체로, ICC/IF에 최적화됨. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공. PBS 기반 저장용액에 40% 글리세롤 포함, 단기 4°C 보관 및 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human IL12RB1 (Recombinant protein control fragment, Product #RP-107995) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662869 |
Product Specific Information
Immunogen sequence:
TSECCFQDPPY PDADSGSASG PRDLRCYRIS SDRYECSWQY EGPTAGVSHF LRCCLSSGRC CYFAAGSATR LQFSDQAGVS VLYTVTLWVE S
Highest antigen sequence identity to the following orthologs:
- Mouse: 45%
- Rat: 46%
Target Information
The protein encoded by this gene is a type I transmembrane protein belonging to the hemopoietin receptor superfamily. It binds to interleukin 12 with low affinity and is part of the IL12 receptor complex. The protein forms disulfide-linked oligomers required for IL12 binding activity. Coexpression with IL12RB2 leads to high-affinity IL12 binding and signaling. Lack of expression results in immunodeficiency associated with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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