Thermo Fisher Scientific NR5A1 Monoclonal Antibody (N1665)
NR5A1(SF-1) 단백질을 특이적으로 인식하는 마우스 단클론 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ELISA 등 다양한 응용에 적합하며, Protein A로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 3 µg/mL | - |
| Immunohistochemistry (IHC) | - | 11 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL | 2 publications |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | - | 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | - | 3 publications |
| ELISA | 0.1 µg/mL | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
| Miscellaneous (PubMed) | - | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N1665 |
| Immunogen | BALB/c mouse immunized with E. coli-expressed recombinant human SF-1 (218–461 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | Physiological saline |
| Contains | 0.1% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long term storage, store at -20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532209 |
Product Specific Information
This antibody specifically recognizes human SF-1 and cross-reacts with mouse and rat SF-1.
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in the development and differentiation of endocrine organs. It is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland.
SF-1 regulates transcription of multiple steroidogenic enzymes from the cytochrome P450 family and contains activation domains AF1 and AF2, which interact with nuclear receptors and coactivators such as SRC-1, GRIP1, CBP, and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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