Thermo Fisher Scientific RXRA Monoclonal Antibody (K8508)
RXRA 단백질을 특이적으로 인식하는 Mouse monoclonal antibody (Clone K8508). Human, Mouse, Rat에 반응하며 WB, IHC, ICC, ELISA, IP, ChIP 등 다양한 응용에 사용 가능. 비결합형 액상 형태로 1 mg/mL 농도, 냉장 보관 권장.
- 카탈로그번호
- 433900
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RXRA Monoclonal Antibody (K8508)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–20 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | - |
| ELISA | 0.1 µg/mL | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
| ChIP assay (ChIP) | Assay-dependent | View 1 publication |
| Gel Shift (GS) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | K8508 |
| Immunogen | Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human RXR-alpha (2–133 aa). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | Physiological saline |
| Contains | 0.1% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532208 |
Product Specific Information
This antibody specifically recognizes human RXR alpha and cross-reacts with mouse and rat RXR alpha. It does not recognize human RXR beta or gamma.
Target Information
Retinoic Acid (RA), the active metabolite of vitamin A, plays a key role in regulating the differentiation of proliferating precursor cells such as carcinoma and neuronal precursors. The Retinoid X Receptors (RXRs) family—RXR alpha, beta, and gamma—preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with other RA receptors. Retinoids may have therapeutic potential in cervical cancer and are known to influence neuronal development, synaptic plasticity, and learning and memory behaviors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.