Thermo Fisher Scientific Cytokeratin 17 Polyclonal Antibody
사이토케라틴 17에 특이적인 토끼 폴리클로날 항체로, WB, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫트에 반응하며 높은 특이성과 재현성을 제공. 항원 친화 크로마토그래피로 정제된 액상 형태로 장기 보관 시 -20°C에서 안정적 유지.
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Thermo Fisher Scientific Cytokeratin 17 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000–1:20,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 83–432 of Human Cytokeratin 17 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.69 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545425 |
Product Specific Information
- Recommended positive controls: HeLa, Rat bladder
- Predicted reactivity: Mouse (96%), Rat (96%), Sheep (95%), Chimpanzee (99%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Cytokeratins are a subfamily of intermediate filament proteins characterized by biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately 40–68 kDa and isoelectric pH between 4.9–7.8.
Each human cytokeratin is numbered 1–20. Expression patterns vary by epithelium type and differentiation stage, making cytokeratin antibodies valuable tools for distinguishing epithelial malignancies.
These antibodies assist in tumor differential diagnosis through immunohistochemistry and are also useful in cytopathology and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-27949_Cytokeratin_17_Q04695-1_Rabbit.svg, PA5-27949_Cytokeratin_17_Q04695-1_Rabbit_PDP.jpeg)
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