Thermo Fisher Scientific PEX5 Polyclonal Antibody
PEX5 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 및 Mouse 시료에 반응합니다. Western Blot과 IHC(P)에서 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 31–311 of Human PEX5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2546523 |
Product Specific Information
- Recommended positive controls: A431
- Predicted reactivity: Mouse (91%), Bovine (97%), Guinea pig (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The PEX5 gene product binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are crucial for assembling functional peroxisomes.
Peroxisome biogenesis disorders (PBDs) are genetically heterogeneous autosomal recessive diseases characterized by multiple peroxisomal function defects.
Defects in this gene are associated with neonatal adrenoleukodystrophy (NALD), Zellweger syndrome (ZWS), and infantile Refsum disease (IRD).
Alternatively spliced transcript variants encoding different isoforms have been identified.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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