Thermo Fisher Scientific OTX2/Orthodenticle homeobox 2 (Transcription Factor) Monoclonal Antibody (PCRP-OTX2-1E10)
OTX2 전사인자에 특이적인 Mouse IgG1 단클론 항체로, Human 시료에 반응합니다. Flow Cytometry, ELISA, IP에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. -20°C 보관, 연구용 전용 제품입니다.
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Thermo Fisher Scientific OTX2/Orthodenticle homeobox 2 (Transcription Factor) Monoclonal Antibody (PCRP-OTX2-1E10)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1–2 µg/100–500 µg total protein |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-OTX2-1E10 |
| Immunogen | Recombinant human full-length OTX2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted to react in Chick, Mouse, Rat, Xenopus, and Zebrafish.
Target Information
OTX2 is a 289 amino acid protein belonging to the bicoid sub-family of homeodomain-containing transcription factors.
It has two known alternative splice variants with distinct isoforms, though other isoforms cannot be excluded.
OTX2 acts as an early marker of endodermal differentiation of embryonic stem cells and may play a role in brain and sensory organ development.
The protein may bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
Defects in OTX2 are associated with microphthalmia syndromic type 5 (MCOPS5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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