Thermo Fisher Scientific OTX2/Orthodenticle homeobox 2 (Transcription Factor) Monoclonal Antibody (PCRP-OTX2-1E10)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

1-2 µg/10^6 cells

-

ELISA (ELISA)

Assay-dependent

-

Immunoprecipitation (IP)

1-2 µg/100-500 µg total protein

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

PCRP-OTX2-1E10

Immunogen

Recombinant human full-lengthOTX2protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OTX2,uniProtId:P32243-1,ncbiNodeId:9606,antigenRange:1-289,antigenLength:289,antigenImageFileName:5015-MSM1-P1ABX_OTX2_P32243-1_House_mouse.svg,antigenImageFileNamePDP:5015-MSM1-P1ABX_OTX2_P32243-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Predicted to react in Chick, Mouse, Rat, Xenopus, Zebrafish

Target Information

OTX2 is a 289 amino acid containing protein encoding a member of the bicoid sub-family of homeodomain-containing transcription factors. It has two known alternative splice variants with distinct isoforms though presence of other isoforms cannot be excluded. The protein is an early marker of endodermal differentiation of embryonic stem cells and may play a role in the development of the brain and the sensory organs. The protein may bind to BCD target sequence (BTS): 5-TCTAATCCC-3. Defects in OTX2 are the cause of microphthalmia syndromic type 5 (MCOPS5).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.