Thermo Fisher Scientific IP3 Receptor 2 Polyclonal Antibody
IP3 Receptor 2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 인간 시료에 반응합니다. 고순도 액상 형태로 제공되며, -20°C에서 보관합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-PIEESNILSPVQD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2932857 |
Product Specific Information
- No cross-reactivity expected with other types of ITPR.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Inositol 1,4,5-trisphosphate (IP3) acts as a second messenger for many growth factors, hormones, and neurotransmitters. Upon binding to IP3 receptor (IP3R), IP3 triggers the release of intracellular calcium into the cytosol. Functional IP3R forms homo- or heterotetramers of ~240 kDa glycoprotein subunits. IP3R is structurally and functionally related to the ryanodine receptor, another intracellular calcium-release channel.
The similarity between IP3R and ryanodine receptor extends to their association with the immunophilin protein FKBP12. Phosphorylation of IP3R by PKC increases IP3-mediated calcium release, while dephosphorylation by calcineurin reduces calcium release, resulting in calcium oscillations. Mammalian IP3R subunits are encoded by three distinct genes with differential expression patterns:
- IP3R-I: heart, liver, kidney, ovary, and Purkinje neurons
- IP3R-II: predominantly in brain
- IP3R-III: pancreatic islets, kidney, and gastrointestinal tract
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific ADORA2A Polyclonal Antibody
681,400원
Thermo Fisher Scientific
Thermo Fisher Scientific PARP12 Polyclonal Antibody
697,000원
Thermo Fisher Scientific
Thermo Fisher Scientific IP3 Receptor 2 Polyclonal Antibody
681,400원
Thermo Fisher Scientific
Thermo Fisher Scientific OMG Polyclonal Antibody
681,400원
Thermo Fisher Scientific
Thermo Fisher Scientific OGFR Polyclonal Antibody
681,400원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|