Thermo Fisher Scientific PARP12 Polyclonal Antibody
PARP12 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody. Western blot 및 ICC/IF에 사용 가능. 고순도(Ammonium sulfate precipitation)로 정제된 액상 제품이며, 인체 반응성. 연구용으로 DNA 손상 관련 PARP12 단백질 분석에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 0.03 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-NAHDIKNKSSAP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932864 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells.
Poly(ADP-ribose) polymerases (PARPs) constitute a large family of 18 proteins encoded by different genes, displaying a conserved catalytic domain. PARP-1 (113 kDa) and PARP-2 (62 kDa) are enzymes whose catalytic activity is stimulated by DNA strand breaks.
Novel PARPs extend the field of poly(ADP-ribosyl)ation to various aspects of cell biology including proliferation and cell death. Some members interact, share partners and subcellular localizations, suggesting fine-tuned regulation of this modification process.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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