Thermo Fisher Scientific ENT1 Polyclonal Antibody
Human ENT1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 ELISA에 적합. 합성 펩타이드(aa 200–300)를 면역원으로 사용. 액상 형태, 1.31 mg/mL 농도, PBS/glycerol buffer에 보관. -20°C 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 200–300 of human SLC29A1 (NP_001071645.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.31 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805339 |
Product Specific Information
- Immunogen Sequence: ELSESAFGYF ITACAVIILT IICYLGLPRL EFYRYYQQLK LEGPGEQETK LDLISKGEEP RAGKEESGVS VSNSQPTNES HSIKAILKNI SVLAFSVCFI F
- Positive Samples: U-87MG
- Cellular Location: Apical cell membrane, Basolateral cell membrane, Cell membrane, Multi-pass membrane protein
Target Information
The ENT1 (SLC29A1) gene belongs to the equilibrative nucleoside transporter family. It encodes a transmembrane glycoprotein localized to plasma and mitochondrial membranes, mediating nucleoside uptake from the extracellular medium. This transporter is sensitive to inhibition by nitrobenzylthioinosine and plays a crucial role in nucleotide synthesis for cells lacking de novo synthesis pathways, as well as in the uptake of cytotoxic nucleosides used in cancer and antiviral therapies. Multiple alternatively spliced variants encoding the same protein have been identified.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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