Thermo Fisher Scientific EphB2 Polyclonal Antibody
EPHB2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 및 다양한 종에 반응합니다. IHC(P)에서 1:100으로 사용 가능하며, 항원 친화 크로마토그래피로 정제된 액상 제품입니다. 신경계 발달 및 혈관 형성 연구에 적합합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rabbit, Rat, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from internal region of human EPHB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550896 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Panda, Rabbit, Opossum, Zebrafish (100%).
Target Information
EPHB2 is a receptor tyrosine kinase belonging to the ephrin receptor family. Members of the Eph family play crucial roles in biological processes such as nervous system development, angiogenesis, and neural synapse formation and maturation.
Ephrins are divided into two classes based on structure and sequence:
- Ephrin-A (EFNA): Anchored to the membrane by glycosylphosphatidylinositol linkage
- Ephrin-B (EFNB): Transmembrane proteins
Eph receptors are similarly grouped based on extracellular domain sequence similarity and ligand binding affinity. Ephrin receptors form the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and is essential for vascular development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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