Thermo Fisher Scientific Plexin A3 Polyclonal Antibody
인간, 생쥐, 랫트 반응성을 가진 Rabbit Polyclonal 항체로 Plexin A3 단백질을 검출. IHC, ICC/IF, ELISA 등 다양한 응용에 적합. Protein A로 정제된 고순도 항체로 안정적인 액상 형태 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Plexin A3, amino acids 101–200 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Plexin A3 acts as a coreceptor for SEMA3A and SEMA3F, essential for class 3 semaphorin signaling and cytoskeletal remodeling. It plays a critical role in axon guidance during neural development and regulates migration of sympathetic neurons. Required for normal dendritic spine morphology in pyramidal neurons, and may influence semaphorin-mediated programmed cell death. Class 3 semaphorins interact with a complex of neuropilin and plexin, where the plexin component modulates affinity and activates downstream signaling.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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