Thermo Fisher Scientific CD21 Recombinant Rabbit Monoclonal Antibody (PD00-23)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA550703 | - | Thermo Fisher Scientific MA550703 CD21 Recombinant Rabbit Monoclonal Antibody (PD00-23) 100 ul pk | 재고문의 | pk | 825,000원 | - | 907,500원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
1:4,000
Immunohistochemistry (PFA fixed) (IHC (PFA))
1:1,000
Immunocytochemistry (ICC/IF)
1:100
Flow Cytometry (Flow)
1:500-1:1,000
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
PD00-23
Immunogen
Synthetic peptide within Human CD21 aa 1000 to the C-terminus. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
CD21,
uniProtId:
P20023-1,
ncbiNodeId:
9606,
antigenRange:
1000-1033,
antigenLength:
1033,
antigenImageFileName:
MA5-50703_CD21_P20023-1_Rabbit.svg,
antigenImageFileNamePDP:
MA5-50703_CD21_P20023-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3092878
Product Specific Information
Positive control: Raji cell lysates, human tonsil tissue, human spleen tissue, Raji, human prostate cancer.
Predicted band size: 113 kDa
Subcellular Location: Cell membrane.
Target Information
CD21 (complement receptor 2, CR2, C3D receptor, EBV receptor) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to follicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands. CD21 functions as receptor for C3d, C3dg and iC3b complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. Genetic variations in the CD21 gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively, spliced transcript variants encoding different isoforms of CD21 have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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