Thermo Fisher Scientific PU.1 Recombinant Rabbit Monoclonal Antibody (PD00-14)
Human PU.1 단백질을 인식하는 Rabbit Recombinant Monoclonal 항체. Western blot과 IHC(Paraffin)에서 검증됨. 핵 내 전사인자 분석에 적합. Protein A 정제, 1 mg/mL 농도, 4°C 또는 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:4,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PD00-14 |
| Immunogen | Synthetic peptide within Human PU.1 (aa 1–100/270) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093005 |
Product Specific Information
- Positive control: Daudi cell lysate, THP-1 cell lysate, human B-cell lymphoma tissue
- Predicted band size: 31 kDa
- Subcellular Location: Nucleus
Target Information
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development.
The nuclear protein binds to a purine-rich sequence known as the PU-box near promoters of target genes and regulates their expression with other transcription factors and cofactors.
It can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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