Thermo Fisher Scientific CDKN2C Recombinant Rabbit Monoclonal Antibody (23GB5650)
CDKN2C 단백질을 인식하는 재조합 토끼 단일클론 항체로 인간, 마우스, 랫트에 반응합니다. Western blot과 유세포분석에 적합하며, 고순도 액상 형태로 제공됩니다. 세포 주기 조절 및 종양 억제 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB5650 |
| Immunogen | A synthesized peptide derived from human CDKN2C (1–110AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. It interacts with CDK4 or CDK6 to prevent activation of CDK kinases, functioning as a cell growth regulator controlling G1 progression.
Ectopic expression suppresses human cell growth correlated with wild-type RB1 function.
Knockout mouse studies indicate roles in spermatogenesis regulation and tumor suppression.
Two alternatively spliced transcript variants encoding an identical protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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