Thermo Fisher Scientific RILPL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RILPL1. Recombinant protein control fragment (Product #RP-97878). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RILPL1,uniProtId:Q5EBL4-1,ncbiNodeId:9606,antigenRange:82-169,antigenLength:403,antigenImageFileName:PA5-59512_RILPL1_Q5EBL4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-59512_RILPL1_Q5EBL4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646562

Product Specific Information

Immunogen sequence: LELDRLRLER MDRIEKERKH QKELELVEDV WRGEAQDLLS QIAQLQEENK QLMTNLSHKD VNFSEEEFQK HEGMSERERQ VMKKLKEV

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

Target Information

Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH. Does not regulate lysosomal morphology and distribution (PubMed:14668488). Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (PubMed:30398148). [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.