Thermo Fisher Scientific BBS2 Polyclonal Antibody
Human BBS2 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol 완충액에 보존. BBS 단백질 복합체 연구 및 Bardet-Biedl syndrome 관련 연구에 적합.
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Applications
Tested Application and Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BBS2. Recombinant protein control fragment (Product #RP-98640). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638488 |
Product Specific Information
Immunogen sequence:
IVTSLCPMYG SRFGYALSNG TVGVYDKTSR YWRIKSKNHA MSIHAFDLNS DGVNELITGW SNGKVDARSD RTGEVIFKDN FSSAIAGVVE GDYRMDG
- Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 96%
Target Information
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation, and mental retardation.
The proteins encoded by BBS gene family members are structurally diverse, and the similar phenotypes exhibited by mutations in BBS gene family members are likely due to their shared roles in cilia formation and function.
Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport.
The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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