Thermo Fisher Scientific VPS37A Polyclonal Antibody
VPS37A 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 IHC(P)에서 검증됨. 인간 시료에 반응하며, ESCRT-I 복합체 연구에 적합. 항원 친화 크로마토그래피로 정제된 고순도 항체.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein of human VPS37A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636609 |
Product Specific Information
This antibody detects endogenous levels of total VPS37A protein.
Target Information
The VPS37A gene belongs to the VPS37 family and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, which is essential for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5, and alternatively spliced transcript variants have been reported.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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