Thermo Fisher Scientific TRPA1 Polyclonal Antibody
TRPA1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, 안정적인 PBS/glycerol buffer 저장. 냉동(-20°C) 보관 권장.
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Thermo Fisher Scientific TRPA1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 900–1000 of human TRPA1 (NP_015628.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.89 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805033 |
Product Specific Information
- Positive Samples: HeLa, Mouse heart
- Cellular Location: Cell membrane, Multi-pass membrane protein
- Immunogen sequence:
SPLLSIIQTF SMMLGDINYR ESFLEPYLRN ELAHPVLSFA QLVSFTIFVP IVLMNLLIGL AVGDIAEVQK HASLKRIAMQ VELHTSLEKK LPLWFLRKVD Q
Target Information
TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction. TRPA1 is a transformation-associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons. Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage. It is also expressed outside of the CNS and is dysregulated during oncogenic transformation. The structure of TRPA1 is related to ankyrin and transmembrane proteins, and it may play roles in signal transduction and growth control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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