Thermo Fisher Scientific AZIN1 Monoclonal Antibody (OTI5C7), TrueMAB
AZIN1 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot에 적합합니다. Human 및 Rat 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. PBS, BSA, 글리세롤 기반 완충액에 보관되며, -20°C에서 냉동 보관이 권장됩니다.
- 카탈로그번호
- TA810908
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 260–448 of human AZIN1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Antizyme inhibitor (AZIN1) is a protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZIN1 acts as an enzymatically inactive ODC homolog that counteracts the inhibitory effects of ODC antizymes (OAZ1, OAZ2, and OAZ3) by competing with ODC for antizyme binding. This process inhibits antizyme-dependent ODC degradation, releases ODC monomers from inactive complexes, and promotes formation of catalytically active ODC homodimers, restoring polyamine production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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