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Thermo Fisher Scientific 53BP1 Polyclonal Antibody
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53BP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC 등 다양한 응용에 적합. 인간 및 비인간 영장류 반응성. DNA 손상 반응 및 종양 억제 연구에 활용 가능. 고순도 항원 친화 크로마토그래피로 정제됨.
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마지막 업데이트 2025. 08. 02. 오후 06:41
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Thermo Fisher Scientific PA517578 53BP1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
542,600원VAT 포함 596,860원
Thermo Fisher Scientific · Thermo Fisher Scientific 53BP1 Polyclonal Antibody
Thermo Fisher Scientific 53BP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | View publication |
| Immunocytochemistry (ICC/IF) | 1:100 | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the center of human 53BP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 26 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10987290 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the sites of double-strand breaks. It may function in checkpoint signaling during mitosis, enhance TP53-mediated transcriptional activation, and participate in DNA repair by maintaining genomic stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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