Thermo Fisher Scientific MRE11 Polyclonal Antibody
MRE11 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫 등 다양한 종에 반응합니다. WB, IHC, IP 등 다중 응용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. DNA 이중가닥 절단 복구 연구용으로 적합합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues surrounding Lys496 of human Mre11A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 163 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10982214 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex, which plays a central role in double-strand break repair, DNA recombination, maintenance of telomere integrity, and meiosis. The complex possesses single-stranded endonuclease activity and double-strand-specific 3'-5' exonuclease activity provided by MRE11. RAD50 is required to bind DNA ends and hold them in close proximity. Mutations in the gene could result in ataxia-telangiectasia-like disorder 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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