Thermo Fisher Scientific LRIG1 Polyclonal Antibody
Thermo Fisher Scientific의 LRIG1 Polyclonal Antibody는 인간 LRIG1 단백질을 인식하는 토끼 유래 다클론 항체로, Western blot, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 보관됩니다. 암 연구 및 세포 신호전달 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LRIG1. Recombinant protein control fragment (Product #RP-90316) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2643468 |
Product Specific Information
Immunogen sequence:
TRKKSEEYSV TNTDETVVPP DVPSYLSSQG TLSDRQETVV RTEGGPQANG HIESNGVCPR DASHFPEPDT HSVACRQPKL CAGSAYHKEP WKAMEKAEGT PGPHKMEHGG RVVCSDCNTE VDCYS
Antigen sequence identity:
Mouse – 74%, Rat – 74%
Target Information
LRIG1 protein (UniProt ID: Q96JA1) is encoded on chromosome band 3p14.3, a region frequently deleted in various human cancers. LRIG1 functions as a tumor suppressor gene and encodes an integral cell-surface membrane protein expressed in various human tissues. The 143-kDa LRIG1 protein may be cleaved into 111-kDa and 32-kDa fragments. Down-regulation of LRIG1 has been implicated in the development and progression of glial and other tumor types.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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