Thermo Fisher Scientific LRIG1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LRIG1. Recombinant protein control fragment (Product #RP-90316). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LRIG1,uniProtId:Q96JA1-1,ncbiNodeId:9606,antigenRange:818-942,antigenLength:1093,antigenImageFileName:PA5-52860_LRIG1_Q96JA1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52860_LRIG1_Q96JA1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643468

Product Specific Information

Immunogen sequence: TRKKSEEYSV TNTDETVVPP DVPSYLSSQG TLSDRQETVV RTEGGPQANG HIESNGVCPR DASHFPEPDT HSVACRQPKL CAGSAYHKEP WKAMEKAEGT PGPHKMEHGG RVVCSDCNTE VDCYS

Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 74%.

Target Information

LRIG1 protein Q96JA1 is coded by a gene on a chromosome band 3p14.3, this region is known to be deleted in various human cancers. LRIG1 is considered to be a tumor suppressor gene in humans. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues and that its 143-kDa form might be cleaved into 111-kDa and 32-kDa fragments. The LRIG1 protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.