Thermo Fisher Scientific QPRT Polyclonal Antibody
인간 QPRT 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 버퍼에 40% 글리세롤 포함, 4°C 보관 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human QPRT. Recombinant protein control fragment (Product # RP-89649) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646187 |
Product Specific Information
Immunogen sequence:
ALVDSWLRED CPGLNYAALV SGAGPSQAAL WAKSPGVLAG QPFFDAIFTQ LNCQVSWFLP EGSKLVPVAR VAEVRGPAHC LLLGERVALN TLARCSGIAS AAAAAVEAAR GAGWTGHVAG TRKTTPGFRLV
- Highest antigen sequence identity to orthologs:
- Mouse: 86%
- Rat: 84%
Target Information
QPRT gene encodes a key enzyme in the catabolism of quinolinate, an intermediate in the tryptophan–nicotinamide adenine dinucleotide pathway. Quinolinate acts as a potent endogenous excitotoxin to neurons. Elevated quinolinate levels in the brain are associated with neurodegenerative disorders such as epilepsy, Alzheimer’s disease, and Huntington’s disease. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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