Thermo Fisher Scientific Phospho-4EBP1 (Thr37, Thr46) Recombinant Rabbit Monoclonal Antibody (5V9O2)
Phospho-4EBP1 (Thr37, Thr46) 인산화 단백질을 검출하는 재조합 토끼 단일클론 항체. Western blot 및 ELISA에 적합하며, 높은 특이성과 재현성을 제공. 단백질 A 정제, PBS/glycerol buffer로 안정적 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:8,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5V9O2 |
| Immunogen | A synthetic phosphorylated peptide around T37 & T46 of human EIF4EBP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.54 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Target Information
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. Phosphorylation of this protein in response to signals such as UV irradiation and insulin signaling leads to its dissociation from eIF4E and activation of mRNA translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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