Thermo Fisher Scientific CDCA4 Polyclonal Antibody
Human CDCA4 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 면역분석에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 buffer에 보관. 세포 증식 및 E2F 관련 전사 조절 연구에 적합.
- 카탈로그번호
- PA563717
- 판매단위
- pk
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Thermo Fisher Scientific CDCA4 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CDCA4. Recombinant protein control fragment (Product #RP-101964). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639574 |
Product Specific Information
Immunogen sequence:
LKTVSSYSLQ RQSLLDMSLV KLQLCHMLVE PNLCRSVLIA NTVRQIQEEM TQDGTWRTVA PQAAERAPLD RLVSTEILCR A
Highest antigen sequence identity to orthologs:
- Mouse – 83%
- Rat – 85%
Target Information
CDCA4 encodes a protein belonging to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation through the E2F/retinoblastoma pathway. It also influences JUN oncogene expression. CDCA4 exhibits nuclear-mitotic apparatus distribution and participates in spindle organization during prometaphase. It may act as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been identified, along with two pseudogenes on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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