Thermo Fisher Scientific CDCA4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CDCA4. Recombinant protein control fragment (Product #RP-101964). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDCA4,uniProtId:Q9BXL8-1,ncbiNodeId:9606,antigenRange:24-104,antigenLength:241,antigenImageFileName:PA5-63717_CDCA4_Q9BXL8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63717_CDCA4_Q9BXL8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639574

Product Specific Information

Immunogen sequence: LKTVSSYSLQ RQSLLDMSLV KLQLCHMLVE PNLCRSVLIA NTVRQIQEEM TQDGTWRTVA PQAAERAPLD RLVSTEILCR A

Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 85%.

Target Information

CDCA4 encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.