Thermo Fisher Scientific CRG-L2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CRG-L2. Recombinant protein control fragment (Product #RP-103354). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CRG-L2,uniProtId:Q6ZMI3-1,ncbiNodeId:9606,antigenRange:79-140,antigenLength:551,antigenImageFileName:PA5-63723_CRG-L2_Q6ZMI3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63723_CRG-L2_Q6ZMI3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640154

Product Specific Information

Immunogen sequence: ASAPPQDPAS SARNKRSHSG EPAPHIRAES HDMLMMMTYS MVPIRVMVDL CNSTKGICLT GP

Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 82%.

Target Information

CRG-L2 is a protein that contains olfactomedin-like and collagen-like domains. The encoded protein, which exists in both transmembrane and secreted forms, promotes formation of the nodes of Ranvier in the peripheral nervous system. Mutations in this gene cause a form of lethal congenital contracture syndrome in human patients. Autoantibodies to the encoded protein have been identified in sera form patients with multifocal motor neuropathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.