Thermo Fisher Scientific MRPS22 Polyclonal Antibody
MRPS22 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 인간 및 마우스 반응성, 고순도 친화 크로마토그래피 정제, -20°C 보관.
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Thermo Fisher Scientific MRPS22 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MRPS22 (Accession P82650), corresponding to amino acid residues D287–Q337 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903355 |
Product Specific Information
Antibody detects endogenous levels of total MRPS22.
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and play a role in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition—opposite to prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins comprising the mitoribosome differ significantly among species, making sequence homology recognition difficult. The MRPS22 gene encodes a 28S subunit protein unique to mammalian mitoribosomes and does not have a counterpart in prokaryotic or fungal-mitochondrial ribosomes. This gene lies telomeric to and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to MRPS22 is located on chromosome Xq.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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