Thermo Fisher Scientific Dynactin 3 Polyclonal Antibody
Dynactin 3 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, IP 등 다양한 응용 가능. E. coli 유래 Human DCTN3 fragment로 면역생성. Unconjugated 형태, 1 mg/mL 농도. 연구용으로만 사용.
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Thermo Fisher Scientific Dynactin 3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1–5 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human DCTN3 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2867055 |
Target Information
This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis.
This subunit exists only as part of the dynactin complex, is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates two transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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