Thermo Fisher Scientific RPL14 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Target Information

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.
This gene encodes a ribosomal protein that is a component of the 60S subunit and belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain and is located in the cytoplasm.

The gene includes a trinucleotide (GCT) repeat tract that is highly polymorphic, resulting in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5′-terminal exons exist but encode the same protein. As typical for ribosomal protein genes, multiple processed pseudogenes are dispersed throughout the genome.

References:
Aoki M., Diabetes 45:157–164 (1996).
Tanaka M., Biochem. Biophys. Res. Commun. 243:531–537 (1998).
Yoshihama M., Genome Res. 12:379–390 (2002).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.