Thermo Fisher Scientific Caspase 3 p17 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.1–0.5 µg/mL
• View 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 0.5–1 µg/mL
• View publications

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

CASP3 (Caspase-3 Apoptosis-Related Cysteine Protease), also known as YAMA, CPP32 or APOPAIN, is a caspase protein that interacts with caspase 8 and caspase 9. It is encoded by the CASP3 gene and is part of the cysteine-aspartic acid protease family.

• Tiso et al. (1996): Localized CPP32 gene to human chromosome 4q33–q35.1.
• Fernandes-Alnemri et al. (1994): Overexpression of CPP32 in insect cells induced apoptosis.
• Tewari et al. (1995): Showed activated Yama cleaved PARP into the 85-kD apoptotic form.

⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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