Thermo Fisher Scientific KRT81 Polyclonal Antibody
Rabbit polyclonal antibody against human KRT81 protein. Suitable for IHC (paraffin) applications with high specificity. Purified by antigen affinity chromatography and supplied in PBS with glycerol. For research use only.
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Applications
Tested Application and Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human KRT81. Recombinant protein control fragment (Product #RP-105621) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663297 |
Product Specific Information
- Immunogen sequence: AESWYRSKCEE MKATVIRHGE TLRRTKEEIN ELN
- Highest antigen sequence identity: Mouse 94%, Rat 91%
Target Information
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein that heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structural similarity.
One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.
All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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