Thermo Fisher Scientific ID3 Monoclonal Antibody (OTI7B6), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Members of the Id family of basic helix-loop-helix (bHLH) proteins include ID1, ID2, ID3, and ID4. These proteins are ubiquitously expressed and dimerize with class A and B HLH proteins. Due to the absence of the basic region, the resulting heterodimers cannot bind DNA, acting as negative regulators of bHLH protein DNA binding. ID proteins modulate muscle-specific gene expression by inhibiting transcription factors such as E12 and MyoD. Their expression is growth factor-dependent, and reduction of ID mRNA delays reentry into the cell cycle following growth factor stimulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.