Thermo Fisher Scientific PVRL1/NECTIN1 Recombinant Rabbit Monoclonal Antibody (BLR274L)
인간 PVRL1/NECTIN1 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot, Flow cytometry, Immunoprecipitation에 사용 가능. HEK293F 발현 시스템에서 생산되며, 고순도 정제된 형태로 제공. 세포 간 접착 및 바이러스 수용체 연구에 적합.
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Thermo Fisher Scientific PVRL1/NECTIN1 Recombinant Rabbit Monoclonal Antibody (BLR274L)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | 1 µL/10^6 cells |
| Immunoprecipitation (IP) | 6 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR274L |
| Immunogen | Recombinant protein representing the extracellular domain of Human PVRL1/NECTIN1 (residues 31–331) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Flow Cytometry: Cells fixed in 4% formaldehyde and permeabilized with 90% methanol.
Target Information
This gene encodes an adhesion protein involved in the organization of adherens and tight junctions in epithelial and endothelial cells. It is a calcium-independent cell-cell adhesion molecule belonging to the immunoglobulin superfamily, with three extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region.
This protein serves as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus, mediating viral entry into epithelial and neuronal cells.
Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome, as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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