Thermo Fisher Scientific PMS1 Polyclonal Antibody
PMS1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태로, 장기 보관 시 -20°C 권장. DNA 불일치 수선 관련 연구에 적합.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PMS1. Recombinant protein control fragment (Product #RP-105847) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662975 |
Product Specific Information
Immunogen sequence:
ESVLIALENLM TTCYGPLPST NSYENNKTDV SAADIVLSKT AETDVLFNKV ESSGKNYSNV DTSVIPFQND MHNDESGKNT DDCLNHQISI GDFGYGHCSS
Highest antigen sequence identity to the following orthologs:
- Mouse: 64%
- Rat: 65%
Target Information
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family.
The PMS1 protein is involved in the repair of DNA mismatches and forms heterodimers with MLH1, another DNA mismatch repair protein.
Mutations in PMS1 are associated with hereditary nonpolyposis colorectal cancer type 3 (HNPCC3), also known as Lynch syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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