Thermo Fisher Scientific Acid Phosphatase 1 Polyclonal Antibody
Thermo Fisher Scientific의 Acid Phosphatase 1 폴리클로날 항체는 Rabbit IgG 기반으로 인간, 소, 돼지에 반응합니다. Western blot에 적합하며, 고순도 Protein G 정제 방식으로 제조되었습니다. PBS와 젤라틴 완충액에 보관되며 연구용으로 사용됩니다.
- 카탈로그번호
- PA141703
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 40–80 of human ACP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.2% gelatin |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2221823 |
Product Specific Information
PA1-41703 detects Acid phosphatase 1, isoform b.
Suggested positive control: antigen standard for ACP1 (transient overexpression lysate), human liver protein, liver lysate.
Target Information
Low molecular weight protein tyrosine phosphatases, including the human red cell phosphatase HCPTP, are widely expressed cytosolic proteins (~18 kDa) existing in distinct isoforms. They are highly selective for phosphotyrosine over phosphoserine or phosphothreonine.
HCPTP-A and HCPTP-B proteins expressed in human red cells and placenta represent fast and slow forms of red cell acid phosphatase. Like other tyrosine phosphatases, HCPTP is inhibited by vanadate and operates via a catalytic mechanism involving a cystinylphosphate intermediate. The crystal structure of bovine heart-derived enzyme BHPTP reveals a four-stranded central parallel β-sheet with flanking α-helices and an active site cysteine residue in the typical tyrosine phosphatase sequence context (CXXXXXR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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