Thermo Fisher Scientific Transthyretin Polyclonal Antibody
Human Transthyretin을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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- PA5110655
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Transthyretin (Product # RP-94759) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856066 |
Product Specific Information
Immunogen sequence:
GTGESKCPLM VKVLDAVRGS PAINVAVHVF RKAADDTWEP FASGKTSESG ELHGLTTEEE FVEGIYKVEI DTKSYWKALG ISPFHEHAEV VFTANDSGPR RYTIAALLSP YSYSTTAVVT NPKE
Target Information
Transthyretin (TTR), also known as prealbumin, is a plasma protein that functions as a transporter of thyroxine and retinol-binding protein. It is primarily produced in the liver and secreted into plasma. TTR constitutes about 25% of cerebrospinal fluid (CSF) protein, suggesting selective transport across the blood-CSF barrier or synthesis within the central nervous system. Transthyretin is associated with neuritic plaques, neurofibrillary tangles, and microangiopathic lesions in senile cerebral amyloid. Over 40 mutations in the TTR gene have been linked to amyloid deposition disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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