Thermo Fisher Scientific EXOSC10 Polyclonal Antibody
인간 EXOSC10 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 사용 가능. 액상 형태이며 항원 친화 크로마토그래피로 정제됨. 4°C 보관, 연구용 전용 제품.
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Thermo Fisher Scientific EXOSC10 Polyclonal Antibody
Applications
- Western Blot (WB): 1:1,000–1:5,000
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 835 to 885 of human Exosome Component 10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
About 50% of patients with polymyositis/scleroderma (PM-Scl) overlap syndrome are reported to have autoantibodies to a nuclear/nucleolar particle termed PM-Scl.
Exosome component 10 (EXOSC10), also named autoantigen PM/Scl-2, is the 100 kDa antigen component of PM-Scl and is recognized by most sera of PM-Scl patients.
EXOSC10 is strongly enriched in the nucleolus, with a small amount found in the cytoplasm, supporting the existence of a nucleolar RNA exosome complex form.
As a putative catalytic component of the RNA exosome complex with 3′→5′ exoribonuclease activity, EXOSC10 participates in numerous cellular RNA processing and degradation events.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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