Thermo Fisher Scientific ROPN1L Polyclonal Antibody
Human ROPN1L 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:2,500–1:5,000 희석으로 사용 가능. AKAP 관련 단백질 연구에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관하며 연구용으로만 사용.
- 카탈로그번호
- PA558689
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific ROPN1L Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:2,500–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ROPN1L. Recombinant protein control fragment (Product #RP-96880). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646699 |
Product Specific Information
Immunogen sequence:IPFKTFSYVY RYLARLDSDV SPLETESYLA SLKENIDARK NGMIGLSDFF FPKRKLLESI ENSEDV
Highest antigen sequence identity to the following orthologs:
- Mouse: 48%
- Rat: 47%
Target Information
Principal Names: ROPN1L; Ropporin-1 like; ASP; AKAP-associated sperm protein
Official Gene Symbol: ROPN1L
Gene ID: 83853 (human)
Gene Map Locus: 5p15.2 (human)
AKAPs act as scaffolding proteins coordinating phosphatase/kinase signaling at the cytoskeleton. They interact with PKAs and anchor them to specific sub-cellular compartments and participate in multiple cellular processes including growth, metabolism, and differentiation.
ASP, a 26 kDa protein, is a novel AKAP-interacting protein. It interacts with the amphipathic helix of AKAP3 and facilitates AKAP3-PKA interactions. It consists of a conserved N-terminal AKAP-binding domain and a central cysteine-rich Fz domain. It is specifically expressed in sperm and may play a significant role in sperm motility and cytoskeletal reorganization during spermiogenesis.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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