Thermo Fisher Scientific NUDT6 Polyclonal Antibody
인간 NUDT6 단백질에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합하며 고순도 항원 친화 크로마토그래피로 정제. 연구용으로 FGF-2 발현 조절 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NUDT6. Recombinant protein control fragment (Product #RP-96737). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644878 |
Product Specific Information
Immunogen sequence:
KSEFRSVLSI RQQHTNPGAF GKSDMYIICR LKPYSFTINF CQEECLRCEW MDLNDLAKTE NTTPITSRVA RLLLYGYREG FDKIDLTVEE LPAVYTGLF
Highest antigen sequence identity to the following orthologs:
- Mouse: 81%
- Rat: 83%
Target Information
NUDT6 (nudix (nucleoside diphosphate linked moiety X)-type motif 6), also known as Antisense basic fibroblast growth factor or GFG-1, is a member of the Nudix hydrolase family of pyrophosphatases. Nudix hydrolases contain a characteristic Nudix domain and catalyze hydrolysis of nucleoside diphosphate derivatives.
The NUDT6 gene is an antisense transcript of FGF-2 and is believed to regulate FGF-2 expression. FGF-2 is a multifunctional heparin-binding growth factor important for angiogenesis, neuroectoderm development, and wound healing.
NUDT6 is expressed as two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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