
Thermo Fisher Scientific IMPDH2 Polyclonal Antibody
IMPDH2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human과 Mouse에 반응하며, 다양한 종에서 예측 반응성을 보입니다. 항원 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 88–291 of Human IMPDH2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.17 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2544970 |
Product Specific Information
- Recommended positive controls: H1299, mouse brain
- Predicted reactivity: Mouse (97%), Rat (96%), Zebrafish (87%), Xenopus laevis (88%), Chicken (90%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis pathway. It maintains cellular guanine deoxy- and ribonucleotide pools required for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate to xanthine-5'-monophosphate, which is subsequently converted to guanosine-5'-monophosphate. This gene is up-regulated in certain neoplasms, suggesting a potential role in malignant transformation.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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